Modelling the impacts of new diagnostic tools for TB in developing countries

Langley, I., Doulla, B., Lin, H.H., Millington, K. and Squire, B., 2012. Modelling the impacts of new diagnostic tools for tuberculosis in developing countries to enhance policy decisions. Health care management science, 15, pp.239-253. [TB0044]

  • Different diagnostic strategies for tuberculosis (TB) may vary in cost-effectiveness based on local factors such as prevalence of HIV, drug resistance, and access to health facilities.
  • The discrete-event simulation (DES) tool helps assess diagnostic methods, particularly for multidrug-resistant TB (MDR-TB), at central reference facilities.
  • DES is useful for policymakers to evaluate the impact of TB diagnostic tools in resource-limited settings, enhancing decision-making processes.
  • Incorporating a disease transmission component into the DES enhances the model’s predictive capabilities, providing insights into TB incidence and its effects on health system and patient outcomes.
  • A visual and interactive DES tool aids national policymakers in validating diagnostic strategies, exploring new approaches, and engaging with simulation outcomes effectively.

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