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Lai, T.C., Chiang, C.Y., Wu, C.F., Yang, S.L., Liu, D.P., Chan, C.C. and Lin, H.H., 2016. Ambient air pollution and risk of tuberculosis: a cohort study. Occupational and environmental medicine, 73(1), pp.56-61.
Respirable risk factors such as active and passive smoking, and indoor air pollution from biomass, potentially impair airway defense mechanisms, increasing TB risk. High levels of ambient air pollution in developing countries correlate with continued high tuberculosis rates, necessitating further investigation into its impact on global TB control. Fine particles and traffic-related pollutants like nitrogen dioxide, nitrogen oxides, and carbon monoxide are linked to a higher risk of active tuberculosis. Laboratory and ecological studies suggest a positive association between ambient air pollution and TB incidence. The true relationship between ambient air pollution and TB might be underestimated due to potential residual confounding by area-level socioeconomic factors.
Tobacco smoking and indoor air pollution from solid-fuel use are primary global risk factors for chronic obstructive pulmonary disease (COPD) and lung cancer. These factors significantly contribute to mortality from these diseases in developing countries. Smoking is an independent risk factor for tuberculosis, exacerbating the spread and severity of the disease. Implementing moderate to complete reductions in smoking and solid-fuel use through tobacco taxation, advertising bans, and fuel pricing could decrease deaths from COPD and lung cancer. Reduction in these risk factors would also significantly decrease tuberculosis incidence by minimizing the duration of infectiousness through effective treatment. These diseases pose substantial economic burdens, particularly in developing countries, due to healthcare costs, reduced labor market participation, and hindered human capital accumulation. The burden is disproportionately higher in low-income or marginalized communities. Programs targeting low-income communities could offer cleaner fuels or stoves, nutritional supplements, and tuberculosis testing coupled with treatment adherence incentives. Tobacco cessation initiatives could be integrated into tuberculosis treatment programs, possibly supported by financial incentives. Revenue from tobacco taxes could subsidize Directly Observed Treatment, Short-course (DOTS), clean energy technologies, and nutrition programs for participating low-income households.
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Lin, H.H., Murray, M., Cohen, T., Colijn, C. and Ezzati, M., 2008. Effects of smoking and solid-fuel use on COPD, lung cancer, and tuberculosis in China: a time-based, multiple risk factor, modelling study. The Lancet, 372(9648), pp.1473-1483.
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