Friday, November 21, 2025

Determinants of Treatment Interruption Among Drug-Resistant Tuberculosis Patients in Medan

Who

  • Participants: 104 bacteriologically confirmed DR-TB patients at H. Adam Malik General Hospital, Medan.

  • Groups: 34 patients lost to follow-up and 70 who continued treatment.

  • Demographics of loss-to-follow-up patients:

    • 65% aged 45–65

    • 55.9% male

    • 91.2% completed high school or equivalent

    • 58.8% employed

    • 70.6% married

What

  • Study focus: Association between perceived social support and perceived quality of healthcare services with loss-to-follow-up among DR-TB patients.

  • Key findings:

    • Low–moderate social support significantly predicts loss-to-follow-up (PR = 14.50; p < 0.001).

    • Patients perceiving only “adequate” healthcare provider support have nearly a six-fold higher risk of loss-to-follow-up compared with those perceiving full support (p < 0.001).

  • Implications: Both social and healthcare support strongly influence treatment adherence and should be integrated into patient-centered TB management strategies in Indonesia.

When

  • The study was conducted over seven months; patients included had initiated treatment between 2020 and 2024.

Where

  • H. Adam Malik Hospital, Medan, Indonesia. 

Why

  • To fill a gap in understanding how combined social support and healthcare service quality predict loss-to-follow-up among DR-TB patients—an area with limited evidence in Medan.

How

  • Design: Observational study using purposive sampling.

  • Inclusion criteria: Age ≥18 years, DR-TB default or treatment completion status, treatment initiation 2020–2024, and informed consent.

  • Data collection: Medical record review plus a validated questionnaire covering demographics, treatment attitude, social support, and healthcare provider support.

  • Instruments: Social support assessed using adapted versions of the MSPSS (Multidimensional Scale of Perceived Social Support) questionnaire (12 items, 3 subscales).

Source: Dalimunthe, A., Sinaga, B.Y.M., Siagian, P. and Amelia, R., 2025. Social Support and Healthcare Service Quality as Determinants of Treatment Interruption Among Drug-Resistant Tuberculosis Patients in Medan, Indonesia. Jurnal Impresi Indonesia, 4(11), pp.5176-5183.

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