Diabetes mellitus (DM) negatively influenced tuberculosis (TB) treatment outcomes. Patients with TB without DM (TB-non-DM) had a lower risk of extended treatment duration and TB recurrence compared to those with TB and DM comorbidity (TB-DM).
The meta-analysis indicated a significantly lower risk of extended treatment duration in TB-non-DM patients compared to TB-DM patients (HR = 0.72, 95% CI: 0.56–0.83, p = .01), with moderate heterogeneity across studies (I² = 59%).
Source: Khattak M, et al. (2024). Tuberculosis (TB) treatment challenges in TB-diabetes comorbid patients: a systematic review and meta-analysis, Annals of Medicine, 56:1, 2313683. https://doi.org/10.1080/07853890.2024.2313683
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