Alvarado-Valdivia, N.T., Flores, J.A., Inolopú, J.L. and Rosales-Rimache, J.A., 2024. Type 2 diabetes mellitus and recurrent Tuberculosis: A retrospective cohort in Peruvian military workers. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 35, p.100432.
· The study
of Type 2 Diabetes Mellitus (DM2) as a risk factor for Tuberculosis (TB) is
complex due to:
- Population
heterogeneity worldwide, including differences in age, access to medical
care, level of glucose control, types and number of complications, and
available medications. See also: https://tbreadingnotes.blogspot.com/2024/07/cost-effectiveness-and-resource.html
· Findings
from the study indicate:
- A higher prevalence of
recurrent TB in military personnel with DM2 compared to those without DM2.
- A more rapid increase
in cumulative risk for recurrent TB among patients with DM2.
- This suggests that
military personnel diagnosed with DM2 may be more predisposed to recurrent
TB. See also: https://tbreadingnotes.blogspot.com/2024/07/tuberculosis-in-healthcare-workers.html
· Contextual
factors to consider:
- In countries with
limited to moderate resources, such as Peru, where both TB and DM2 are
prevalent, military personnel with DM2 may be at increased risk due to
fieldwork exposure. See also: https://tbreadingnotes.blogspot.com/2024/07/ambient-air-pollution-and-risk-of.html
- Despite these
findings, the relationship between DM2 and recurrent TB in military
personnel was not statistically significant.
· Study
limitations:
- The follow-up duration
of three to nine months may have underestimated the recurrence rate. See also: https://tbreadingnotes.blogspot.com/2024/07/feasibility-of-achieving-2025-who.html
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