Tuberculosis mortality in Brunei Darussalam

Chaw L, Jeludin NH, Thu K. Prevalence and risk factors associated with tuberculosis mortality in Brunei Darussalam. Asian Pac J Trop Med 2023; 16(1): 9-15.

It is generally assumed that a country’s TB burden status is positively associated with its TB-related mortality rate. However, previous reports do not fully support this assumption. Over a 5-year study period, we observed an overall TB mortality rate of 8.9% (95% CI: 7.4%-10.8%) in Brunei Darussalam. Significant risk factors for TB mortality included advancing age, female gender, renal disease, and cancer. Our finding that female gender was positively associated with TB mortality contrasts with other studies, where male gender was reported as a risk factor. Furthermore, most TB deaths were not directly related to TB itself, underscoring the importance of clinicians considering non-TB aspects of a patient's history, such as the presence of comorbidities.

 

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