Prevalence of Various Forms of Active Tuberculosis in Patients with Diabetes

Tariq, M., Zafar, S., Waheed, A., Afzal, N., Razzaq, R. and Batool, F., 2023. Prevalence of Various Forms of Active Tuberculosis in Patients with Diabetes. THE THERAPIST (Journal of Therapies & Rehabilitation Sciences), pp.33-37.

Pathophysiological Mechanisms Linking Diabetes Mellitus (DM) to Tuberculosis (TB):

  • Diminished cellular immunity in DM patients.
  • Impaired alveolar macrophage function.
  • Reduced interferon gamma levels.
  • Pulmonary microangiopathy.
  • Inadequate micronutrient levels.

Bidirectional Relationship Between TB and DM:

  • TB and DM coexistence highlights the interaction between a communicable and a non-communicable disease.
  • The co-occurrence is particularly significant in low and middle-income nations.

Increased TB Risk in DM Patients:

  • Higher prevalence of various forms of active tuberculosis in patients with diabetes.
  • DM exacerbates the burden of TB, creating a dual health challenge.

 

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