Association of DM, smoking, and alcohol use with subclinical-to-symptomatic spectrum of TB
Hamada, Y., Quartagno, M., Law, I., Malik, F., Bonsu, F.A., Adetifa, I.M., Adusi-Poku, Y., D'Alessandro, U., Bashorun, A.O., Begum, V. and Lolong, D.B., 2023. Association of diabetes, smoking, and alcohol use with subclinical-to-symptomatic spectrum of tuberculosis in 16 countries: an individual participant data meta-analysis of national tuberculosis prevalence surveys. EClinicalMedicine, 63. [TB0042] · WHO recommends systematic screening for active TB in specific populations or settings. · Screening aims to identify both symptomatic and asymptomatic TB cases. · Males are more likely to have TB but are underrepresented in screenings. · Surveys should systematically collect NCD-related variables to develop TB risk prediction models. · History of TB, HIV, self-reported diabetes, and current smoking can indicate higher TB risk. · The risk magnitude is approximately 1.5-fold for current smoking and self-reported diabetes. · S